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Index > Protein center > DHH(Gene name) > Human
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  • DHH (Gene name),
  • Desert hedgehog protein (Protein name ),  DHH_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    DHH;
    Protein name:
    Desert hedgehog protein(DHH);
    Alternative:
    HHG-3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
    Subcellular Location:
    Desert hedgehog protein C-product Secreted extracellular space The C-terminal peptide diffuses from the cell.
    Protein Attributes:
    Sequence length:
    396
    Sequence:
    50:
    MALLTNLLPL | CCLALLALPA | QSCGPGRGPV | GRRRYARKQL | VPLLYKQFVP | 
    100:
    GVPERTLGAS | GPAEGRVARG | SERFRDLVPN | YNPDIIFKDE | ENSGADRLMT | 
    150:
    ERCKERVNAL | AIAVMNMWPG | VRLRVTEGWD | EDGHHAQDSL | HYEGRALDIT | 
    200:
    TSDRDRNKYG | LLARLAVEAG | FDWVYYESRN | HVHVSVKADN | SLAVRAGGCF | 
    250:
    PGNATVRLWS | GERKGLRELH | RGDWVLAADA | SGRVVPTPVL | LFLDRDLQRR | 
    300:
    ASFVAVETEW | PPRKLLLTPW | HLVFAARGPA | PAPGDFAPVF | ARRLRAGDSV | 
    350:
    LAPGGDALRP | ARVARVAREE | AVGVFAPLTA | HGTLLVNDVL | ASCYAVLESH | 
    396:
    QWAHRAFAPL | RLLHALGALL | PGGAVQPTGM | HWYSRLLYRL | AEELLG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human DHH
    Cat.:
    E1016h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human DHH
    Cat.:
    E1016m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human DHH
    Cat.:
    U1016h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human DHH
    Cat.:
    U1016m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human DHH
    Cat.:
    P1016Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human DHH
    Cat.:
    P1016Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human DHH
    Monoclonal Antibody for Human DHH
    Protein for Human DHH
    Protein for Human DHH

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Expression of Sonic hedgehog and its receptor Patched/Smoothened in human cancer cell lines and embryonic organs."
      Tate G. , Kishimoto K. , Mitsuya T.
      J. Biochem. Mol. Biol. Biophys.4:27-34(2000)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    3. 3.
      "Human desert hedgehog."
      Drummond I.A.
      Submitted (1996-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 85-178
      tissue: Kidney.
    4. 4.
      "A novel mutation of desert hedgehog in a patient with 46,XY partial gonadal dysgenesis accompanied by minifascicular neuropathy."
      Umehara F. , Tate G. , Itoh K. , Yamaguchi N. , Douchi T. , Mitsuya T. , Osame M.
      Am. J. Hum. Genet.67:1302-1305(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PGD
    5. 5.
      "Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP."
      Bishop B. , Aricescu A.R. , Harlos K. , O'Callaghan C.A. , Jones E.Y. , Siebold C.
      Nat. Struct. Mol. Biol.16:698-703(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 39-194 IN COMPLEX WITH HHIP AND ZINC IONS;CALCIUM-BINDING;DOMAIN;INTERACTION WITH HHIP
    6. 6.
      "All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner."
      Kavran J.M. , Ward M.D. , Oladosu O.O. , Mulepati S. , Leahy D.J.
      J. Biol. Chem.285:24584-24590(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 24-189 IN COMPLEXES WITH BOC; CDON; ZINC AND CALCIUM IONS;DOMAIN;INTERACTION WITH BOC AND CDON
    7. 7.
      "Mutations in the desert hedgehog (DHH) gene in patients with 46,XY complete pure gonadal dysgenesis."
      Canto P. , Soederlund D. , Reyes E. , Mendez J.P.
      J. Clin. Endocrinol. Metab.89:4480-4483(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GDXYM PRO-162
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
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